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STAT5B, Mouse, Clone: A4B9, Abnova™

Product Code. 16291600
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Quantity:
500 μg
Unit Size:
500µg
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16291600 500 μg 500µg
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Product Code. 16291600 Supplier Abnova Supplier No. MAB6426.500ug

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Description

Mouse monoclonal antibody raised against synthetic phosphopeptide of STAT5B.

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq

Specifications

Antigen STAT5B
Applications ELISA
Classification Monoclonal
Clone A4B9
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against synthetic phosphopeptide of STAT5B.
Dilution ELISA (1 ug/mL) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from 10mM PBS, pH 7.0
Gene STAT5B
Gene Alias STAT5
Gene Symbols STAT5B
Host Species Mouse
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T694 of human STAT5B.
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6777
Test Specificity Reactive to the immunogen and peptide-BSA conjugating.
Target Species Human
Content And Storage Store at -20°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
Isotype IgG1 κ
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