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TLR5, Mouse, Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a partial recombinant TLR5.

Brand:  Abnova H00007100-A01.50uL

Product Code. 16166725

  • € 242.00 / 50µL

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Description

Description

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene product is expressed in myelomonocytic cells, and recognizes bacterial flagellin, a principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB and stimulates tumour necrosis factor-alpha production. [provided by RefSeq

Sequence: LPPGVFSHLTALRGLSLNSNRLTVLSHNDLPANLEILDISRNQLLAPNPDVFVSLSVLDITHNKFICECELSTFINWLNHTNVTIAGPPADIYCVYPDSFSGVSLFSLSTEGCDEEEV
Specifications

Specifications

TLR5
Polyclonal
Mouse polyclonal antibody raised against a partial recombinant TLR5.
TLR5
FLJ10052/MGC126430/MGC126431/SLEB1/TIL3
Mouse
50 μL
Primary
Human
Antisera
ELISA, Western Blot
Unconjugated
50% glycerol
NM_003268
TLR5
TLR5 (NP_003259, 517 a.a. ∽ 634 a.a) partial recombinant protein with GST tag.
RUO
7100
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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