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TNFSF9, Mouse, Polyclonal Antibody, Abnova™
Mouse polyclonal antibody raised against a partial recombinant TNFSF9.
Brand: Abnova H00008744-A01.50uL
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Description
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction
Sequence: FQLELRRVVAGEGSGSVSLALHLQPLRSAAGAAALALTVDLPPASSEARNSAFGFQGRLLHLSAGQRLGVHLHTEARARHAWQLTQGATVLGLFRVTPEIPAGLPSPRSESpecifications
| TNFSF9 | |
| Polyclonal | |
| Mouse polyclonal antibody raised against a partial recombinant TNFSF9. | |
| TNFSF9 | |
| 4-1BB-L/CD137L | |
| Mouse | |
| 50 μL | |
| Primary | |
| Human | |
| Antisera |
| ELISA, Western Blot | |
| Unconjugated | |
| 50% glycerol | |
| NM_003811 | |
| TNFSF9 | |
| TNFSF9 (NP_003802, 145 a.a. ∽ 254 a.a) partial recombinant protein with GST tag. | |
| RUO | |
| 8744 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
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