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TP53I3, Mouse, Clone: 10A2, Abnova™
Mouse monoclonal antibody raised against recombinant TP53I3.
Brand: Abnova MAB1974.100ug
This item is not returnable.
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Description
The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Specifications
| TP53I3 | |
| Monoclonal | |
| Unconjugated | |
| Western blot (5 to 10 ug/mL) The optimal working dilution should be determined by the end user. | |
| TP53I3 | |
| TP53I3 | |
| Recombinant protein of human TP53I3. | |
| RUO | |
| 9540 | |
| Liquid |
| Western Blot | |
| 10A2 | |
| Mouse monoclonal antibody raised against recombinant TP53I3. | |
| In PBS (0.08% sodium azide) | |
| PIG3 | |
| Mouse | |
| 100 μg | |
| Primary | |
| Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
|
| IgG1 |
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