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ZAP70, Mouse, HRP, Clone: SBZAP, Abnova™
Mouse monoclonal antibody raised against partial recombinant ZAP70.
Brand: Abnova MAB5890.1mL
This item is not returnable.
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Description
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq
Specifications
| ZAP70 | |
| Monoclonal | |
| Lot specific | |
| Mouse monoclonal antibody raised against partial recombinant ZAP70. | |
| In PBS, pH 7.4 (50% glycerol) | |
| FLJ17670/FLJ17679/SRK/STD/TZK/ZAP-70 | |
| Mouse | |
| 1 mL | |
| Primary | |
| human TCR ζ; Zap-70 (Mr 70 KDa). | |
| Store in the dark at 4°C. For long term storage store at -20°C. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing. |
|
| IgG1 κ |
| ELISA, Flow Cytometry | |
| SBZAP | |
| HRP | |
| ELISA (1:1000-1:2000) The optimal working dilution should be determined by the end user. | |
| ZAP70 | |
| ZAP70 | |
| Recombinant protein corresponding to amino acids 280-309 of human ZAP70. | |
| RUO | |
| 7535 | |
| Human | |
| Liquid |
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