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ACROBiosystems Mouse IL-3 R alpha / CD123 Protein, His Tag

Product Code. 16437739
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Quantity:
1 mg
100 μg
Unit Size:
100µg
1mg
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16437739 1 mg 1mg
16427739 100 μg 100µg
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Product Code. 16437739 Supplier ACROBiosystems Supplier No. ILAM52H41mg

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Description

SPR verified

Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.4 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Specifications

Accession Number NP_032395.1
Molecular Weight (g/mol) 36.4 kDa
Quantity 1 mg
Source Mouse IL-3 R alpha, His Tag (ILA-M52H4) is expressed from human 293 cells (HEK293). It contains AA Ser 17- Lys 331 (Accession # P26952-1).
Immunogen Ser 17- Lys 331
Storage Requirements -20°C
Gene Alias IL3R,IL3RA,IL-3 Ra,IL-3 R-alpha,IL3RAY,IL3RX,IL3RY,CD123 antigen,CD123,hIL3Ra,hIL-3 Ra,MGC34174,IL-3 R alpha
Common Name IL-3 R alpha
Conjugate Unconjugated
Species Mouse
Protein Tag His Tag
Buffer PBS, pH7.4
Endotoxin Level Less than 1.0 EU / μg by the LAL method.
Expression System HEK293
Form Powder
Protein Subtype Bio-Markers and CD Antigens
Purity or Quality Grade >95% as determined by SDS-PAGE
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