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STEMCELL Technologies Mouse Recombinant IL-17A

Product Code. 17159401
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Quantity:
100 μg
25 μg
Unit Size:
100µg
25µg
This item is not returnable. View return policy

Product Code. 17159401

Brand: STEMCELL Technologies 78033

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This item is not returnable. View return policy

Description

Interleukin 17A

  • Interleukin 17A (IL-17A) is the founding member of the family of cytokines that includes Interleukin 17B through Interleukin 17F
  • It is a potent proinflammatory cytokine that plays a key role in defense against pathogens
  • IL-17A and IL-17F signal as homodimers or heterodimers through the same receptor, and activate NF-kB, MAPK, and C/EBP pathways
  • IL-17A receptor is expressed on a variety of cell types, including hematopoietic cell compartments
  • IL-17A is produced by T helper 17 cells, CD8+ T cells, γδ T cells, natural killer T cells, B cells, neutrophils, innate lymphoid cells and mesenchymal stromal cells (MSCs)
  • IL-17A receptor is expressed at particularly high levels on stromal cells, including MSCs
  • IL-17A increases the frequency and the average size of colony-forming units-fibroblast derived from bone marrow, as well as the proliferation of bone marrow-derived MSCs

Specifications

Name CTLA-8, IL-17, Interleukin-17, Interleukin-17A
Quantity 100 μg
Cell Type B Cells; Lymphocytes; T Cells; T Cells, CD4+; T Cells, CD8+
Purity or Quality Grade ≥95%
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