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Invitrogen™ MRCK beta Polyclonal Antibody
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Product Code. 16613905
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Quantity:
100 μL
Unit Size:
100µL
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16613905 100 μL 100µL
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Product Code. 16613905 Supplier Invitrogen™ Supplier No. PA599655

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MRCKbeta.

CDC42BPB is a serine/threonine kinases which functions in actin cytoskeleton assembly and organization. Myotonic dystrophy kinaserelated Cdc42-binding (DMPK-like) kinases-alpha and beta (MRCK-alpha, beta) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle Myosin light chain and influences Actin-Myosin contractility. MRCK-alpha can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/Cofilin and to Actin cytoskeletal reorganization. MRCK-alpha can also influence neurite outgrowth promoted by Cdc42 and Rac.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRCK beta
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CDC42BPB
Gene Accession No. Q9Y5S2
Gene Alias CDC42 binding protein kinase beta; CDC42 binding protein kinase beta (DMPK-like); CDC42-binding protein kinase beta; CDC42-binding protein kinase beta (DMPK-like); CDC42BPB; cdc42bpb {ECO:0000312; CDC42BP-beta; DMPK-like beta; EMBL:AAP34403.1}; Kiaa1124; MRCK beta; MRCKb; myotonic dystrophy kinase related CDC42 binding kinase beta; myotonic dystrophy kinase-related CDC42-binding kinase beta; myotonic dystrophy protein kinase like beta; myotonic dystrophy protein kinase-like beta; serine/threonine-protein kinase MRCK beta
Gene Symbols CDC42BPB
Host Species Rabbit
Immunogen A synthesized peptide derived from human CDC42BPB(Accession Q9Y5S2), corresponding to amino acid residues G1645-H1695.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9578
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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