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Invitrogen™ MRGD Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5100957
This item is not returnable.
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Description
Antibody detects endogenous levels of total MRGRD.
May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i). Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
Specifications
| MRGD | |
| Polyclonal | |
| Unconjugated | |
| MRGPRD | |
| Beta-alanine receptor; G protein-coupled receptor MrgD; Gm499; G-protein coupled receptor TGR7; MAS related GPR family member D; mas-related G protein-coupled MRGD; Mas-related G protein-coupled receptor d; MAS-related gene D; MAS-related GPR, member D; mas-related G-protein coupled receptor member D; MAS-related G-protein coupled receptor, member D; Mgrd; MrgD; MRGD G protein-coupled receptor; MRGPRD; TGR7 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 116512 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q8TDS7 | |
| MRGPRD | |
| A synthesized peptide derived from human MRGPRD(Accession Q8TDS7), corresponding to amino acid residues G280-A321. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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