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MRP2 Antibody (M2III-6), Novus Biologicals™
Mouse Monoclonal Antibody
Brand: Novus Biologicals NBP1-42349
This item is not returnable.
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Description
MRP2 Monoclonal specifically detects MRP2 in Human, Rat samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Specifications
| MRP2 | |
| Monoclonal | |
| 0.1 mg/ml | |
| Western Blot 1:20-1:50, Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:20-1:50, Immunohistochemistry-Paraffin 1:20, Immunohistochemistry-Frozen 1:20 | |
| ATP-binding cassette, sub-family C (CFTR/MRP), member 2, Canalicular multidrug resistance protein, canalicular multispecific organic anion transporter 1, CMOAT1, CMOATABC30, CMRP, DJS, KIAA1010, MRP2ATP-binding cassette sub-family C member 2, Multidrug resistance-associated protein 2 | |
| Mouse | |
| Protein G purified | |
| RUO | |
| Primary | |
| M2III-6 reacts with an internal epitope of cMOAT/MRP2, a 170-180 kD transmembrane protein known as the canalicular multi-organic anion transporter, absent in patients with the Dubin-Johnson syndrome, an autosomal recessive liver disorder characterized by chronic conjugated hyperbilirubinemia. cMOAT/MRP2 is closely related to the multidrug resistance related protein MRP, and cMOAT/MRP2 overexpression has been observed in a subset of cisplatin resistant cell lines. M2III-6 was raised against a bacterial fusion protein of cMOAB/MRP2, containing the 202-amino acid COOH terminal end of the protein. M2III-6 did not cross react with the human MDR1, MRP1, MRP3 and MRP5 gene products. | |
| Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | |
| IgG2a |
| Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin) | |
| M2III-6 | |
| Unconjugated | |
| Q92887 | |
| ABCC2 | |
| The antibody reacts with the MRP2 antigen. | |
| 0.2 mL | |
| ABC Transporters, Amino Acids Drugs and other small molecules, Cancer, Diabetes Research, Lipid and Metabolism | |
| 1244 | |
| Human, Rat | |
| Supernatant |
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