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Invitrogen™ MRP6 Monoclonal Antibody (M6II-31)

Description
Recommended positive controls: Liver, kidney and cell Lines (drug-sensitive parental cell lines and their multidrug-resistant derivatives)..
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.
Specifications
Specifications
| Antigen | MRP6 |
| Applications | Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | M6II-31 |
| Concentration | Conc. Not Determined |
| Conjugate | Unconjugated |
| Formulation | tissue culture supernatant with 1% BSA and 0.1% sodium azide |
| Gene | ABCC6 |
| Gene Accession No. | O95255 |
| Gene Alias | ABC34; Abcc1b; ABCC6; Anthracycline resistance-associated protein; ARA; ATP binding cassette subfamily C member 6; ATP-binding cassette sub-family C member 6; ATP-binding cassette, subfamily C (CFTR/MRP), member 6; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; ATP-binding cassette, sub-family C, member 6; DCC; dyscalc; Dyscalc1; EST349056; GACI2; liver multidrug resistance-associated protein 6; Mlp1; MLP-1; MOATE; MOAT-E; Mrp6; MRP-like protein 1; Multidrug resistance-associated protein 6; multidrug resistance-associated protein-6; multi-specific organic anion transporter E; PXE; PXE1; URG7; URG7 protein; multidrug resistance-associated protein 6 |
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