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Description
Immunogen sequence: KQVRVQFCPF EKNVESTRTF LQTVSSEKVR STNLNCSVIA DVRHDGSEPC VDVLFGDGHR LIMRGAHLTA LE Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL53 encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 1p.
Specifications
Specifications
| Antigen | MRPL53 |
| Applications | Immunohistochemistry (Paraffin), Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | MRPL53 |
| Gene Accession No. | Q96EL3 |
| Gene Alias | 1110007K17Rik; 39S ribosomal protein L53, mitochondrial; L53MT; Mitochondrial large ribosomal subunit protein mL53; mitochondrial ribosomal protein L53; MRPL53; MRP-L53 |
| Gene Symbols | MRPL53 |
| Show More |
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