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Invitrogen™ MRPS18B Polyclonal Antibody
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Product Code. 13415617
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Quantity:
100 μL
Unit Size:
100µL
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13415617 100 μL 100µL
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Product Code. 13415617 Supplier Invitrogen™ Supplier No. PA531099

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A431. Predicted reactivity: Human (99%), Mouse (86%), Rat (85%), Pig (90%), Rhesus Monkey (94%), Chimpanzee (98%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRPS18B
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.84 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene MRPS18B
Gene Accession No. Q9Y676
Gene Alias 2400002C15Rik; 28S ribosomal protein S18-2, mitochondrial; 28S ribosomal protein S18b, mitochondrial; C6orf14; HSPC183; HumanS18a; mitochondrial ribosomal protein S18-2; mitochondrial ribosomal protein S18B; Mitochondrial small ribosomal subunit protein bS18b; Mitochondrial small ribosomal subunit protein mS40; MRP-S18-2; MRPS18-2; MRPS18B; MRP-S18-b; mrps18-b; PTD017; S18amt; S18mt-b
Gene Symbols MRPS18B
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human MRPS18B. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 28973
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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