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Invitrogen™ MSI2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA521145
This item is not returnable.
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Description
A suggested positive control is EL4 cell lysate. PA5-21145 can be used with blocking peptide PEP-1259.
Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels.
Specifications
| MSI2 | |
| Polyclonal | |
| Unconjugated | |
| MSI2 | |
| 1700105C15Rik; AI451722; AI563628; AW489193; MSI2; Msi2h; musashi homolog 2; musashi RNA binding protein 2; musashi RNA-binding protein 2; Musashi2; musashi-2; RGD1560397; RNA-binding protein Musashi homolog 2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 124540, 360596, 76626 | |
| 4°C | |
| Liquid |
| Immunohistochemistry, Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| Q920Q6, Q96DH6 | |
| MSI2 | |
| A 15 amino acid peptide near the amino terminus of human MSI2. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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