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MSL2 Mouse anti-Human, Clone: OTI6C10, lyophilized, TrueMAB™

Product Code. 17621622
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Quantity:
100 μg
Unit Size:
100µg
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17621622 100 μg 100µg
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Product Code. 17621622 Supplier Origene Technologies Supplier No. CF811182

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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at ′Lys-35′ (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at ′Lys-4′ (H3K4me) and ′Lys-79′ (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.

Specifications

Antigen MSL2
Applications Western Blot
Classification Monoclonal
Clone OTI6C10
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene MSL2
Gene Accession No. Q9HCI7
Gene Alias MSL-2, MSL2L1, RNF184
Gene Symbols MSL2
Host Species Mouse
Immunogen Full length human recombit protein of human MSL2 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55167
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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