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Invitrogen™ MT-ND3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5103274
This item is not returnable.
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Description
Antibody detects endogenous levels of total MT-ND3.
NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by trans-location of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 3 (ND3) localizes to the hydrophobic protein fragment of complex I. Mutations in the gene encodiing for ND3 may be associated with Parkinson disease.
Specifications
| MT-ND3 | |
| Polyclonal | |
| Unconjugated | |
| MT-ND3 | |
| 1.6.5.3; mitochondrially encoded NADH dehydrogenase 3; Mtnd3; mt-Nd3; NADH dehydrogenase subunit 3; NADH3; NADH-ubiquinone oxidoreductase chain 3; ND3 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 17718, 26199, 4537 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P03897, P03899, P05506 | |
| MT-ND3 | |
| A synthesized peptide derived from human MT-ND3(Accession P03897), corresponding to amino acid residues L15-F65. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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