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Invitrogen™ MT-ND5 Polyclonal Antibody
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Product Code. 16529781
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Quantity:
100 μL
Unit Size:
100µL
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16529781 100 μL 100µL
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Product Code. 16529781 Supplier Invitrogen™ Supplier No. PA596945

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Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse heart, Mouse brain, Rat brain; Cellular Location: Mitochondrion inner membrane, Multi-pass membrane protein Immunogen sequence: IALELNNLTM KLSMNKANPY SSFSTLLGFF PSIIHRITPM KSLNLSLKTS LTLLDLIWLE KTIPKSTSTL HTNMTTLTTN QKGLIKLYFM SFLINIILII ILYSINLE.

A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 5 (ND5) is most likely a component of the hydrophobic protein fragment of Complex I. Mutations in the gene encoding for ND5 are implicated in Mitochondrial neurogastrointestinal encephalomyopathy, an autosomal recessive multisystem disorder that results in dramatically elevated levels of circulating thymidine and deoxyuridine.
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Specifications

Antigen MT-ND5
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.75 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MT-ND5
Gene Accession No. P03915, P03921, P11661
Gene Alias mitochondrially encoded NADH dehydrogenase 5; MTND5; mt-Nd5; NADH Dehydrogenase 5; NADH dehydrogenase subunit 5; NADH5; NADH-ubiquinone oxidoreductase chain 5; ND5
Gene Symbols MT-ND5, ND5
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 500-607 of mouse MT-ND5 (NP_9043381).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17721, 26202, 4540
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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