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Invitrogen™ MTBP Polyclonal Antibody
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Product Code. 16576721
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Quantity:
100 μL
Unit Size:
100µL
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16576721 100 μL 100µL
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Product Code. 16576721 Supplier Invitrogen™ Supplier No. PA588497

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MDRYLLLVIW GEGKFPSAAS REAEHGPEVS SGEGTENQPD FTAANVYHLL KRSISASINP EDSTFPACSV GGIPGSKKWF FAVQAIYGFY QFCSSDWQEI HFDTEKDKIE DVLQTNIEEC LGAVECFEEE DSNSRESLSL ADLYEEAAEN LHQLSDKLPA PGRAMVDIIL LLSDKDPPKL KDYLPTVGAL KHLREWYSAK ITIAGNHCEI NCQKIAEYLS ANVVSLEDLR NVIDSKELWR GKIQIWERKF GFEISFPEFC LKGVTLKNFS TSNLNTDFLA KKIIPSKDKN ILPKVFHYYG; Positive Samples: Mouse spleen.

MTBP inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. The protein may play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. The protein inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MTBP
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Mtbp
Gene Accession No. Q8BJS8
Gene Alias AI429604; hdm2; HDMX; hMTBP; MDM2 (mouse double minute 2)-binding protein, 104kD; MDM2 binding protein; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein binding protein, 104kDa; Mdm2, transformed 3T3 cell double minute p53 binding protein; mdm2-binding protein; MDM2BP; MGC5370; MGC71221; mMTBP; Mtbp; RGD1565672
Gene Symbols Mtbp
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MTBP (NP_0713282).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 105837
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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