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Invitrogen™ MTHFD1L Polyclonal Antibody

Description
Immunogen sequence: HGSLEAALQC LFQRKGSMTM SIQWKTRQLQ SKLHEADIVV LGSPKPEEIP LTWIQPGTTV LNCSHDFLSG KVGCGS Highest antigen sequence indentity to the following orthologs: Rat - 76%, Mouse - 76%.
One-carbon substituted forms of tetrahydrofolate (THF) are involved in the de novo synthesis of purines and thymidylate and support cellular methylation reactions through the regeneration of methionine from homocysteine. MTHFD1L is an enzyme involved in THF synthesis in mitochondria (Christensen et al., 2005 [PubMed 15611115]).
Specifications
Specifications
| Antigen | MTHFD1L |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | MTHFD1L |
| Gene Accession No. | Q6UB35 |
| Gene Alias | 10-formyl-THF synthetase; 2410004L15Rik; AI647056; dJ292B18.2; Formyltetrahydrofolate synthetase; formyltetrahydrofolate synthetase domain containing 1; FTHFSDC1; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; monofunctional C1-tetrahydrofolate synthase, mitochondrial; MTC1THFS; MTHFD1L |
| Gene Symbols | MTHFD1L |
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