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Invitrogen™ MTHFR Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5140282
This item is not returnable.
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Description
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: EELTSEESVF EVFVLYLSGE PNRNGHKVTC LPWNDEPLAA ETSLLKEELL RVNRQGILTI NSQPNINGKP SSDPI Highest antigen sequence indentity to the following orthologs: Rat - 89%, Mouse - 88%.
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
Specifications
| MTHFR | |
| Polyclonal | |
| Unconjugated | |
| MTHFR | |
| 5,10-methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase (NADPH); AI323986; Methylenetetrahydrofolate reductase; methylenetetrahydrofolate reductase (NAD(P)H); MTHFR; RP11-56N19.4 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 4524 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| P42898 | |
| MTHFR | |
| Recombinant protein corresponding to Human MTHFR. Recombinant protein control fragment (Product #RP-109540). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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