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Invitrogen™ MTNR1A Polyclonal Antibody

Description
Positive Samples: U-87MG, Mouse small intestine, Rat small intestine, Rat kidney; Cellular Location: Cell membrane, Multi-pass membrane protein.
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Specifications
Specifications
| Antigen | MTNR1A |
| Applications | ELISA, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1.57 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.09% sodium azide; pH 7.3 |
| Gene | MTNR1A |
| Gene Accession No. | P48039, P49218, Q61184 |
| Gene Alias | mel1a melatonin receptor; mel1a receptor; Mel-1A-R; melatonin receptor 1A; melatonin receptor type 1A; MelR; MR; MT1; Mtnr1a |
| Gene Symbols | MTNR1A |
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