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MTOR Monoclonal Antibody (OTI10A2), TrueMAB™, OriGene

Product Code. 17506133
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100 μL
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30µL
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17506133 100 μL 100µL
17526133 30 μL 30µL
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Product Code. 17506133 Supplier Origene Technologies Supplier No. TA806066

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Description

Mouse Monoclonal Antibody

Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation. Mutations affecting the gene results in Smith-Kingsmore syndrome.

Specifications

Antigen MTOR
Applications Western Blot
Classification Monoclonal
Clone OTI10A2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene MTOR
Gene Accession No. P42345
Gene Alias FRAP, FRAP1, FRAP2, RAFT1, RAPT1, SKS
Gene Symbols MTOR
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 1766-2144 of human MTOR produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2475
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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