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Invitrogen™ MUC4 Recombinant Rabbit Monoclonal Antibody (HL1486)
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Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA547062

Product Code. 17859365

  • € 474.00 / 100µL

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Description

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

Nearly all mucosal surfaces are protected by mucin transmembrane glycoproteins, from bronchioles to corneas to reproductive tracts. Mucin 4 (MUC4) is membrane-bound and is important in protecting and lubricating. MUC4 expression is erroneous in many carcinomas and sarcomas, including fibromyoxoid sarcoma and pancreatic adenocarcinoma. Immunohistochemical staining for MUC4 has been discussed as a potential biomarker for detection of these cancers. MUC4 seems to be most predominantly affected in Asian diseases - Taiwanese infertility and endometriosis, as well as gallstone formation in Chinese men, are connected to MUC4, where similar diseases in other populations do not share these MUC4 mutations. Because MUC4 is so important in mucosal surface protection, it is not surprising that it has been implicated as failing in many metastatic cancer invasions.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MUC4
Recombinant Monoclonal
1 mg/mL
PBS with no preservative
Q8JZM8, Q99102
MUC4
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Mucin 4. The exact sequence is proprietary.
100 μL
Primary
Human, Mouse
Antibody
IgG
Immunohistochemistry (Paraffin), Western Blot
HL1486
Unconjugated
MUC4
4933405I11Rik; Ascites sialoglycoprotein; Ascites sialoglycoprotein 1; Ascites sialoglycoprotein 2; ASGP; ASGP1; ASGP-1; ASGP-2; HSA276359; MUC4; MUC-4; mucin 4; mucin 4, ASGP; mucin 4, cell surface associated; mucin 4, tracheobronchial; Mucin4; mucin-4; Mucin-4 alpha chain; Mucin-4 beta chain; Pancreatic adenocarcinoma mucin; pre-sialomucin complex; Psmc; sialomucin ascites sialoglycoprotein-1; sialomucin complex; testis mucin; Tracheobronchial mucin
Rabbit
Protein A
RUO
140474, 4585
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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