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Invitrogen™ MYCBP2 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA584393
This item is not returnable.
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Description
Immunogen sequence: CYHPAKPFQS QLPSVKEGIS EDLPVKMPCL YLQTLARHHH ENFVGYQDDN LFQDEMRYLR STSVPAPYIS VTPDASPNVF EEPESNMKSM PPSL Highest antigen sequence indentity to the following orthologs: Rat - 97%, Mouse - 98%.
This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, highwire and RPM-1) family of proteins. The encoded protein plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, this protein regulates the cAMP and mTOR signaling pathways, and may additionally regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients and a mutation in this gene has been identified in patients with a rare inherited vision defect.
Specifications
| MYCBP2 | |
| Polyclonal | |
| Unconjugated | |
| MYCBP2 | |
| AU023734; AW107953; AW546647; C130061D10Rik; E3 ubiquitin-protein ligase MYCBP2; Highwire; KIAA0916; MYC binding protein 2; MYC binding protein 2, E3 ubiquitin protein ligase; Myc-binding protein 2; Mycbp2; Myc-bp2; PAM; pam, highwire, rpm 1; pam/highwire/rpm-1 protein; Phr; Phr1; probable E3 ubiquitin-protein ligase MYCBP2; protein associated with Myc; Protein Magellan; R75243 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 23077 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Immunofluorescence | |
| 0.10 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| O75592 | |
| MYCBP2 | |
| Recombinant protein corresponding to Human MYCBP2. Recombinant protein control fragment (Product #RP-108434). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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