Invitrogen™ Mycobacterium tuberculosis 16 kDa Monoclonal Antibody (G06I)

Description

MA1-7065 detects the Mycobacterium tuberculosis. This antibody recognizes the 16kDa antigen (HspX) of Mycobacterium tuberculosis and M. bovis. MA1-7065 has been successfully used in ELISA and Western blot procedures. The MA1-7065 immunogen is M. tuberculosis lysate.

Tuberculosis is a chronic bacterial infection which remains one of the leading killers of young adults world wide. Mycobacterium tuberculosis enters the alveoli by airborne transmission. They are engulfed by alveolar macrophages but resist destruction. Although the exact mechanism is not known, it is suspected that that Mycrobacterium tuberculosis survives by preventing the fusion of the phagosome and lysosome. As the bacterium accumulates it forms a tubercle, spreads to the lymph nodes and becomes a systemic infection. Although treatments for tuberculosis do exist, new strains of Mycobacterium tuberculosis that appear to have multiple-drug resistance (MDR) pose a considerable threat to public health.