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Invitrogen™ Myeloperoxidase Recombinant Rabbit Monoclonal Antibody (RM407)
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Description
This antibody may also react to mouse or rat MPO, as predicted by immunogen homology.
Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.
Specifications
Specifications
| Antigen | Myeloperoxidase |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | RM407 |
| Concentration | 0.01 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 50% glycerol and 0.09% sodium azide |
| Gene | MPO |
| Gene Accession No. | P05164 |
| Gene Alias | 84 kDa myeloperoxidase; 89 kDa myeloperoxidase; mKIAA4033; MPO; Myeloperoxidase; Myeloperoxidase heavy chain; Myeloperoxidase light chain |
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