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Invitrogen™ Myeloperoxidase Recombinant Rabbit Monoclonal Antibody (6Z3W9)

Description
Positive test controls include: HL-60. Immunogen sequence: GVSEPLKRKG RVGPLLACII GTQFRKLRDG DRFWWENEGV FSMQQRQALA QISLPRIICD NTGITTVSKN NIFMSNSYPR DFVNCSTLPA LNLASWREAS.
Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.
Specifications
Specifications
| Antigen | Myeloperoxidase |
| Applications | ELISA, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | 6Z3W9 |
| Concentration | 1.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3 |
| Gene | MPO |
| Gene Accession No. | P05164 |
| Gene Alias | 84 kDa myeloperoxidase; 89 kDa myeloperoxidase; mKIAA4033; MPO; Myeloperoxidase; Myeloperoxidase heavy chain; Myeloperoxidase light chain |
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