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Myogenin Antibody (MGN185 + F5D), Alexa Fluor™ 594, Novus Biologicals™
Mouse Monoclonal Antibody
Brand: Novus Biologicals NBP2-34684AF594
This item is not returnable.
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Description
Myogenin Monoclonal specifically detects Myogenin in Human, Mouse, Rat, Porcine, Feline samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Specifications
| Myogenin | |
| Monoclonal | |
| Alexa Fluor 594 | |
| 50 mM sodium borate with 0.05% sodium azide | |
| MYOG | |
| Human Myogenin recombinant protein (MGN185); Rat Myogenin recombinant fragment containing amino acid 30-224 (F5D) (Uniprot: P15173) | |
| 0.1 mL | |
| Primary | |
| Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80% amino acid homology in their bHLH motifs.Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms' tumor. | |
| Store at 4°C in the dark. |
| Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin) | |
| MGN185 + F5D | |
| Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen | |
| BHLHC3, bHLHc3Myogenic factor-4; myogenin, Class C basic helix-loop-helix protein 3, myf-4, MYF4myogenin, Myogenic factor 4, MYOGENIN, myogenin (myogenic factor 4) | |
| Mouse | |
| Protein A or G purified | |
| Cancer, Stem Cell Markers, Transcription Factors and Regulators | |
| 4656.0 | |
| Human, Mouse, Rat, Pig, Feline | |
| IgG1 κ |
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