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Myopodin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16824035 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16824035 20 μL 20µL
16814035 150 μL 150µL
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Product Code. 16824035 Supplier Proteintech Supplier No. 254531AP20UL

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Description

Rabbit Polyclonal Antibody

SYNPO2 was initially identified as myopodin, a member of the synaptopodin family that contains one PPXY motif and multiple PXXP motifs. It colocalizes with alpha-actinin and is found at the Z-disc and during stress conditions will translocate to the nucleus, suggesting that it is part of signaling pathways in addition to its function as a structural protein. SYNPO2 has been shown to bind to calmodulin, alpha-actinin, and smooth muscle myosin and will stimulate actin polymerization in a calmodulin dependent manner, consistent with its proposed role in organizing the cytoskeleton. While deletion of SYNPO2 has been reported to be highly correlated with the invasiveness of prostate cancers, other reports suggest that down-regulation of SYNPO2 reduces the invasiveness and motility of prostate cancer cells.

Specifications

Antigen Myopodin
Applications Western Blot
Classification Polyclonal
Concentration 0.27 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene SYNPO2
Gene Accession No. D4A702, Q91YE8, Q9UMS6
Gene Alias Genethonin 2, Myopodin, synaptopodin 2, SYNPO2
Gene Symbols SYNPO2
Host Species Rabbit
Immunogen Myopodin Fusion Protein Ag22176
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 118449, 171024, 499702
Target Species Mouse, Rat, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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