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N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS, packaged under Argon in resealable ChemSeal™ bottles

Product Code. 11394978
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25 g
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Product Code. 11394978 Supplier Thermo Scientific Alfa Aesar Supplier No. 043928.14
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Estimated Shipment: 19-10-2026
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CAS: 25561-30-2 | C8H18F3NOSi2 | 257.403 g/mol

N,O-Bis(trimethylsilyl)trifluoroacetamide is used for analytical purposes or as a chemical reagent for synthesis of more complex molecules. It is silylation reagent useful in GC and GC-MS for the derivatization of a wide range of functional groups under mild conditions. It is also used as DAT inhibitor and a SLC6A2 inhibitor. It is routinely used to derivatize carboxylic acids, phenols, steroids, amines, alcohols, and alkaloids and amides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

  • Packaged under Argon
TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 25561-30-2
Molecular Formula C8H18F3NOSi2
Molecular Weight (g/mol) 257.403
MDL Number MFCD00008269
InChI Key XCOBLONWWXQEBS-GHXNOFRVSA-N
Synonym bstfa, n,o-bis trimethylsilyl trifluoroacetamide, acetamide, 2,2,2-trifluoro-o,n-bis trimethylsilyl, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl acetimidate, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl ethanimidate, trimethylsilyl 1z-2,2,2-trifluoro-n-z-trimethylsilyl ethanimidoate #, n,o-bis trimethylsilyl trifluoroacetamide bstfa, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl ethanecarboximidate
PubChem CID 9601896
IUPAC Name trimethylsilyl (1Z)-2,2,2-trifluoro-N-trimethylsilylethanimidate
SMILES C[Si](C)(C)N=C(C(F)(F)F)O[Si](C)(C)C

Spezifikation

Melting Point -10°C
Color Colorless to Yellow
Density 0.97 g/mL
Boiling Point 145°C to 147°C
Flash Point 23°C (73°F)
Packaging ChemSeal™ bottles
Refractive Index 1.384
Quantity 25 g
UN Number UN2924
Beilstein 3607620
Sensitivity Moisture sensitive
Solubility Information Soluble in water (hydrolyses),chloroform and hexane.
Formula Weight 257.4
Physical Form Liquid
Chemical Name or Material N,O-Bis (trimethylsilyl)trifluoroacetamide, With 1% TMCS
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Produktidentifikator
  • N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS, packaged under Argon in resealable ChemSeal bottles
Signalwort
  • Warning
Gefahrenkategorie
  • Serious eye damage/eye irritation Category 2
  • Flammable liquid Category 3
  • Skin corrosion/irritation Category 2
Gefahrenhinweis
  • H226-Flammable liquid and vapour.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • EUH014-Reacts violently with water.
Sicherheitshinweis
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
Ergänzende Informationen
  • MIXTURE LIST-Contain: N,O-Bis(trimethylsilyl)trifluoroacetamide

RUO – Research Use Only

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