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Invitrogen™ NAE1 Polyclonal Antibody
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Product Code. 16548161
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Quantity:
100 μL
Unit Size:
100µL
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16548161 100 μL 100µL
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Product Code. 16548161 Supplier Invitrogen™ Supplier No. PA592174

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAQLGKLLKE QKYDRQLRLW GDHGQEALES AHVCLINATA TGTEILKNLV LPGIGSFTII DGNQVSGEDA GNNFFLQRSS IGKNRAEAAM EFLQELNSDV SGSFVEESPE NLLDNDPSFF CRFTVVVATQ LPESTSLRLA DVLWNSQIPL LICRTYGLVG YMRIIIKEHP VIESHPDNAL EDLRLDKPFP ELREHFQSYD LDHMEKKDHS HTPWIVIIAK; Positive Samples: SH-SY5Y, BT-474, HL-60, SW620, NIH/3T3, Mouse brain, Mouse lung, Rat brain; Cellular Location: Cell membrane.

The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NAE1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.59 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene NAE1
Gene Accession No. Q13564, Q8VBW6, Q9Z1A5
Gene Alias 59kDa; A-116A10.1; amyloid beta precursor protein binding protein 1, 59kDa; amyloid beta precursor protein-binding protein 1, 59 kDa; amyloid beta precursor protein-binding protein 1, 59kD; amyloid protein-binding protein 1; Appbp1; APP-BP1; HPP1; Nae1; NEDD8 activating enzyme E1 subunit 1; NEDD8-activating enzyme E1 regulatory subunit; NEDD8-activating enzyme E1 subunit; protooncogene protein 1; proto-oncogene protein 1; ula-1
Gene Symbols NAE1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NAE1 (NP_0038961).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 234664, 84019, 8883
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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