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Invitrogen™ NALP10 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA523311
This item is not returnable.
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Description
The amino acid sequence used as immunogen is 95% homologous in rabbit and 86% homologous in mouse. Immunogen sequence: REVQRLLEVK EQEGNDE.
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1-b, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1-b processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation.
Specifications
| NALP10 | |
| Polyclonal | |
| Unconjugated | |
| NLRP10 | |
| 6430548I20Rik; CLR11.1; NACHT, leucine rich repeat and PYD containing 10; NACHT, LRR and PYD containing protein 10; NACHT, LRR and PYD domains-containing protein 10; NACHT/LRR/pyrin domain-containing protein 10; NALP10; Napl10; neuronal apoptosis inhibitor protein 10; NLR family pyrin domain containing 10; NLR family, pyrin domain containing 10; NLRP10; NOD8; Nucleotide-binding oligomerization domain protein 8; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10; PAN5; Pynod | |
| Rabbit | |
| Protein A | |
| RUO | |
| 244202, 338322 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| PBS with 0.05% BSA and 0.05% sodium azide | |
| Q86W26, Q8CCN1 | |
| NLRP10 | |
| A portion of amino acids 493-509 of human NALP10 protein. | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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