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Invitrogen™ NALP11 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA561235

Product Code. 15779051

  • € 566.00 / 100µL

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Description

Description

Immunogen sequence: HLGNDGVAKL LESLISPDCV LKVVGLPLTG LNTQTQQLLM TVKERKPSLI FLSETWSLKE GREIGVTPAS QPGSIIPNSN LDYMFFKFPR MSAAMRTSNT ASR Highest antigen sequence identity to the following orthologs: Mouse - 23%, Rat - 23%.

NALP11 is a 1033 amino acid containing cytoplasmic protein belonging to the NLRP family with a DAPIN domain, six LRR (leucine-rich) repeats and a NACHT domain. Reports suggest that it is a short NALP involved in inflammation potential. NALP proteinsare implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes. The DAPIN domain is necessary and sufficient for suppression of NF-kappa B activation induced by TNF and for inducing IL-1B secretion in collaboration with Caspase-1. It is involved in interaction with PYCARD.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

NALP11
Polyclonal
Unconjugated
NLRP11
CLR19.6; NACHT, leucine rich repeat and PYD containing 11; NACHT, LRR and PYD domains-containing protein 11; NALP11; NLR family pyrin domain containing 11; NLR family, pyrin domain containing 11; NLRP11; NOD17; Nucleotide-binding oligomerization domain protein 17; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 11; PAAD- and NACHT-containing protein 10B; PAAD-and NACHT domain-containing protein 10; PAN10; PYPAF6; PYPAF7; PYRIN-containing APAF1-like protein 6
Rabbit
Antigen affinity chromatography
RUO
204801
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.2 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
P59045
NLRP11
Recombinant protein corresponding to Human NALP11. Recombinant protein control fragment (Product #RP-99200).
100 μL
Primary
Human
Antibody
IgG
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