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Invitrogen™ NALP5 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA585953

Product Code. 16302865

  • € 520.00 / 100µL

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Description

Description

NALP5 Polyclonal Antibody for ICC/IF

NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

NALP5
Polyclonal
Unconjugated
NLRP5
CLR19.8; MATER; Mater protein; Mater protein homolog; maternal antigen that embryos require; NACHT, leucine rich repeat and PYD containing 5; NACHT, LRR and PYD domains-containing protein 5; Nalp5; NLR family pyrin domain containing 5; NLR family, pyrin domain containing 5; NLRP5; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5; Ooplasm-specific protein 1; OP1; PAN11; PYPAF8
Rabbit
Antigen affinity chromatography
RUO
126206, 23968
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunocytochemistry
1 mg/mL
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
P59047, Q9R1M5
NLRP5
Synthetic peptide within mouse MATER aa 1,114-1,163.
100 μL
Primary
Human, Mouse
Antibody
IgG
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