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Invitrogen™ NAMPT Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA11045
Description
PA1-1045 detects Visfatin (PBEF) in human samples. PA1-1045 has been successfully used in Western blot procedures. In Western blot analysis of human adipose tissue lysate this antibody detects a ~52 kDa protein representing Visfatin. The PA1-1045 immunogen is a synthetic peptide corresponding to residues S (472) F D E I R K N A Q L N I E L E A A H H (491) of human Visfatin.
Visfatin, also known as pre-B cell colony-enhancing factor, is an adipocytokine that is abundantly secreted by visceral adipose tissue, with insulin mimetic effects. Visfatin mimics insulin signaling by binding to the insulin receptor and reducing glucose release from liver cells, while stimulating glucose utilization in adipocytes and myocytes. Visfatin is also invoved in enhancement of cell proliferation, biosynthesis of nicotinamide mono-and dinucleotide and glucose homeostasis.
Specifications
| NAMPT | |
| Polyclonal | |
| Unconjugated | |
| NAMPT | |
| 1110035O14Rik; AI314458; AI480535; DKFZp666B131; EC 2.4.2.12; hypothetical protein; MGC117256; NAmPRTase; NAMPT; nampt1; nampta; NAMPTP1; Nicotinamide phosphoribosyltransferase; nicotinamide phosphoribosyltransferase 1; nicotinamide phosphoribosyltransferase a; nicotinamide phosphoribosyltransferase pseudogene 1; PBEF; Pbef1; pre-B cell-enhancing factor; pre-B-cell colony enhancing factor 1; pre-B-cell colony-enhancing factor 1; Pre-B-cell colony-enhancing factor 1 homolog; pre-B-cell colony-enhancing factor 1 precursor; VF; VISFATIN | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 10135 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 1 mg/mL BSA and 0.05% sodium azide | |
| P43490 | |
| NAMPT | |
| Synthetic peptide corresponding to residues S (472) F D E I R K N A Q L N I E L E A A H H (491) of human Visfatin. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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