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Invitrogen™ NAPSA Recombinant Rabbit Monoclonal Antibody (PD01-30)
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Product Code. 17920063
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Quantity:
100 μL
Unit Size:
100µL
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17920063 100 μL 100µL
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Product Code. 17920063 Supplier Invitrogen™ Supplier No. MA550741

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Description

Rabbit Recombinant Monoclonal Antibody

Positive control: Human lung carcinoma tissue, human kidney tissue. Predicted band size: 45 kDa Subcellular Location: Secreted.

Napsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body. Napsin 1 processes surfactant protein B in healthy pulmonary and renal tissues, but is abnormally regulated when carcinogenesis occurs. Thus, many researchers have found napsin evaluation to be useful in identifying several cancers, and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin can be used as a specific biomarker for differentiation of carcinoma types. Napsin has also been associated with pulmonary alveolar proteinosis as well as in protein catabolism in renal tubules.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NAPSA
Applications Immunohistochemistry (Paraffin)
Classification Recombinant Monoclonal
Clone PD01-30
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene NAPSA
Gene Accession No. O96009
Gene Alias asp 4; ASP4; Aspartyl protease 4; KAP; Kdap; KDAP-1; kidney-derived aspartic protease-like protein; Nap; NAP1; NAPA; Napsa; napsin A aspartic peptidase; napsin-1; Napsin-A; pronapsin; pronapsin A; SNAPA; TA01/TA02
Gene Symbols NAPSA
Host Species Rabbit
Immunogen Recombinant fragment within Human NAPSA aa 1-150.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9476
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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