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NAT1 Monoclonal Antibody (OTI4E9), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA810654
This item is not returnable.
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Description
Arylamine N-acetyltransferases (NAT-1 and NAT-2) catalyze N- or O-acetylation of heterocyclic and arylamine substrates in the detoxification of a wide array of drugs. Certain alleles causing high N-acetyltransferase activity have been associated with colon and urinary bladder cancers, as NATs also bioactivate several known carcinogens. Both NAT-1 and NAT-2 are cytoplasmic proteins and play an active role in the detoxification of many arylamine and hydrazine drugs. N-acetylation polymorphism is determined by the level of NAT activity in liver tissues, and has been linked to the action and toxicity of drugs that contain amines. Human NAT-1 is the functional homolog of rodent NAT-2, while human NAT-2 is the functional homolog of rodent NAT-1.Specifications
| NAT1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P18440 | |
| NAT1 | |
| Full length human recombit protein of human NAT1 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| OTI4E9 | |
| Unconjugated | |
| NAT1 | |
| AAC1, MNAT, NAT-1, NATI | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 9 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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