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Invitrogen™ NBL1 Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA547972
This item is not returnable.
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Description
In direct ELISAs, approximately 25% cross-reactivity with recombinant mouse (rm) DAN is observed and less than 1% cross-reactivity with recombinant chicken Caronte, rmGremlin, and recombinant human Cerberus 1 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.
This gene product is the founding member of the evolutionarily conserved CAN family of proteins, which contain a domain resembling the CTCK motif found in a number of signaling molecules. These proteins are secreted, and act as BMP antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Specifications
| NBL1 | |
| Polyclonal | |
| Unconjugated | |
| Nbl1 | |
| D1S1733E; D4H1S1733E; DAN; DAN domain family member 1; Dana; DAND1; differential screening-selected gene aberrant in neuroblastoma; N03; NB; Nbl1; neuroblastoma 1, DAN family BMP antagonist; neuroblastoma candidate region, suppression of tumorigenicity 1; neuroblastoma suppressor of tumorigenicity 1; neuroblastoma, suppression of tumorigenicity 1; Neuroblastoma, suppression of tumorigenicity 1 (DNA segment human D1S1733E); NO3; Protein N03; Zinc finger protein DAN | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 4681 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| Immunohistochemistry, Neutralization, Western Blot | |
| 0.2 mg/mL | |
| PBS with 5% trehalose and No Preservative | |
| P41271 | |
| Nbl1 | |
| Mouse myeloma cell line NS0-derived recombinant human DAN Ala17-Asp180 (Ala36Arg). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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