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NBN Monoclonal Antibody (OTI7D5), TrueMAB™, OriGene
Description
The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
Specifications
Specifications
| Antigen | NBN |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Clone | OTI7D5 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 50% glycerol and 0.02% sodium azide |
| Gene | NBN |
| Gene Accession No. | O60934 |
| Gene Alias | AT-V1, AT-V2, ATV, NBS, NBS1, P95 |
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Product Title
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