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Invitrogen™ NBS1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA586459
This item is not returnable.
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Description
Purity is > 95% by SDS-PAGE.
The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
Specifications
| NBS1 | |
| Polyclonal | |
| Unconjugated | |
| NBN | |
| AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 27354, 4683, 85482 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
| O60934, Q9JIL9, Q9R207 | |
| NBN | |
| Synthetic peptide, corresponding to amino acids 241-290 of Human Nibrin. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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