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Invitrogen™ NCF2 Polyclonal Antibody
Sheep Polyclonal Antibody
Brand: Invitrogen™ PA5149409
This item is not returnable.
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Description
Reconstitute at 0.2 mg/mL in sterile PBS.
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). Defects in NCF2 are a cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 2 (CGD2). Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.
Specifications
| NCF2 | |
| Polyclonal | |
| Unconjugated | |
| NCF2 | |
| 67 kDa neutrophil oxidase factor; chronic granulomatous disease, autosomal 2; EMBL:FAA00361.1}; FLJ93058; NADPH oxidase activator 2; NADPH oxidase subunit (67 kD); NADPH oxidase subunit (67kDa); NCF2; NCF-2; ncf2 {ECO:0000312; neutrophil cytosol factor 2; neutrophil cytosolic factor 2; neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2); neutrophil NADPH oxidase factor 2; Noxa2; p67phox; p67-phox | |
| Sheep | |
| Antigen affinity chromatography | |
| RUO | |
| 4688 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| Western Blot | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| P19878 | |
| NCF2 | |
| E. coli-derived recombinant human p67phox, Lys355-Val526 (His389Gln). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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