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Invitrogen™ NCF2 Polyclonal Antibody
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Product Code. 30534311
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Quantity:
100 μg
Unit Size:
100µg
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30534311 100 μg 100µg
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Product Code. 30534311 Supplier Invitrogen™ Supplier No. PA5149409

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Description

Sheep Polyclonal Antibody

Reconstitute at 0.2 mg/mL in sterile PBS.

NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). Defects in NCF2 are a cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 2 (CGD2). Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.
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Specifications

Antigen NCF2
Applications Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with trehalose and no preservative
Gene NCF2
Gene Accession No. P19878
Gene Alias 67 kDa neutrophil oxidase factor; chronic granulomatous disease, autosomal 2; EMBL:FAA00361.1}; FLJ93058; NADPH oxidase activator 2; NADPH oxidase subunit (67 kD); NADPH oxidase subunit (67kDa); NCF2; NCF-2; ncf2 {ECO:0000312; neutrophil cytosol factor 2; neutrophil cytosolic factor 2; neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2); neutrophil NADPH oxidase factor 2; Noxa2; p67phox; p67-phox
Gene Symbols NCF2
Host Species Sheep
Immunogen E. coli-derived recombinant human p67phox, Lys355-Val526 (His389Gln).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4688
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Lyophilized
Isotype IgG
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