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Description
This antibody detects both isoforms of ND1, 318aa 34-36 kDa and 268aa, 28-30 kDa.
A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7),while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer′s disease and Parkinson disease.
Specifications
Specifications
| Antigen | ND1 |
| Applications | Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.28 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | MT-ND1 |
| Gene Accession No. | P03886 |
| Gene Alias | MT ND1, MTND1, NADH dehydrogenase subunit 1, NADH1, ND1 |
| Gene Symbols | mt-Nd1 |
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Product Title
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