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NDUFAF2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13891-1-AP-20UL
This item is not returnable.
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Description
Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80% of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-kappa-B-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I.Specifications
| NDUFAF2 | |
| Polyclonal | |
| Unconjugated | |
| NDUFAF2 | |
| B17.2 like, B17.2L, mimitin, Mimitin, mitochondrial, MMTN, NDUFA12 like protein, NDUFA12L, NDUFAF2 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 361894, 75597, 91942 | |
| -20°C | |
| Liquid |
| Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunoprecipitation, Immunocytochemistry | |
| 0.13 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q8N183 | |
| Ndufaf2 | |
| NDUFAF2 Fusion Protein Ag4853 | |
| 20 μL | |
| Primary | |
| Mouse, Rat, Human | |
| Antibody | |
| IgG |
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