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Invitrogen™ NDUFB1 Polyclonal Antibody

Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
NDUFB1 (NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1), also known as CI-MNLL (complex I-MNLL), CI-SGDH or NADH-ubiquinone oxidoreductase MNLL subunit, is a 58 amino acid single-pass membrane protein that localizes to the matrix side of the mitochondrial membrane. A member of the complex I NDUFB1 subunit family, NDUFB1 is encoded by a gene that maps to human chromosome 14q32.12. Chromosome 14 houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder alpha1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
Specifications
Specifications
| Antigen | NDUFB1 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | NDUFB1 |
| Gene Accession No. | O75438, P0DN34, P0DN35 |
| Gene Alias | CI-MNLL; CI-SGDH; complex I MNLL subunit; complex I-MNLL; MNLL; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1; NADH:ubiquinone oxidoreductase subunit B1; NADH-ubiquinone oxidoreductase MNLL subunit; Ndufb1 |
| Gene Symbols | NDUFB1 |
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