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Invitrogen™ NDUFS1 Recombinant Rabbit Monoclonal Antibody (8M0X4)

Description
Immunogen sequence: VEIEKAPKVV AACAMPVMKG WNILTNSEKS KKAREGVMEF LLANHPLDCP ICDQGGECDL QDQSMMFGND RSRFLEGKRA VEDKNIGPLV KTIMTRCIQC TRCIRFASEI AGVDDLGTTG RGNDMQVGTY IEKMFMSELS GNIIDICPVG ALTSKPYAFT ARPWETRKTE SIDVMDAVGS NIVVSTRTGE VMRILPRMHE DINEEWISDK T.
The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.
Specifications
Specifications
| Antigen | NDUFS1 |
| Applications | ELISA, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | 8M0X4 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3 |
| Gene | NDUFS1 |
| Gene Accession No. | P28331, Q66HF1, Q91VD9 |
| Gene Alias | 5830412M15Rik; 9930026A05Rik; CI-75k; CI-75kD; complex I 75kDa subunit; complex I, mitochondrial respiratory chain, 75-kD subunit; complex I-75kD; MGC26839; mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit; NADH dehydrogenase (ubiquinone) Fe-S protein 1; NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa; NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase); NADH:ubiquinone oxidoreductase core subunit S1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; NDUFS1; NDUFS-1; OTTHUMP00000206345; PRO1304 |
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