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Invitrogen™ NDUFS4 Polyclonal Antibody
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Product Code. 16538311
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Quantity:
100 μL
Unit Size:
100µL
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16538311 100 μL 100µL
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Product Code. 16538311 Supplier Invitrogen™ Supplier No. PA592940

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAAVSMSVVL RQTLWRRRAV AVAALSVSRV PTRSLRTSTW RLAQDQTQDT QLITVDEKLD ITTLTGVPEE HIKTRKVRIF VPARNNMQSG VNNTKKWKME FDTRERWENP LMGWASTADP LSNMVLTFST KEDAVSFAEK NGWSYDIEER KVPKPKSKSY GANFSWNKRT RVSTK; Positive Samples: HepG2, 293T, mouse brain, mouse heart, SW620, MCF7, Mouse bone marrow, Mouse liver, Rat brain, Rat liver; Cellular Location: Matrix side, Mitochondrion inner membrane, Peripheral membrane protein.

This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NDUFS4
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.37 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NDUFS4
Gene Accession No. O43181, Q5XIF3, Q9CXZ1
Gene Alias 6720411N02Rik; AQDQ; C1-18k; CI-18; CI-18 kDa; CI-AQDQ; complex I 18kDa subunit; complex I-18 kDa; Complex I-AQDQ; mitochondrial respiratory chain complex I (18-KD subunit); NADH dehydrogenase (ubiquinone) Fe-S protein 4; NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial; NADH:ubiquinone oxidoreductase subunit S4; NADH-ubiquinone oxidoreductase 18 kDa subunit; NDUFS4
Gene Symbols NDUFS4
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-175 of human NDUFS4 (NP_0024861).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17993, 4724, 499529
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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