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Invitrogen™ Neurofascin Polyclonal Antibody
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Product Code. 15527962
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Quantity:
100 μg
Unit Size:
100µg
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15527962 100 μg 100µg
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Product Code. 15527962 Supplier Invitrogen™ Supplier No. PA547468

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Description

Chicken Polyclonal Antibody

This antibody detects human, mouse, rat Neurofascin in Western blots and rat Neurofascin in direct ELISAs. Reconstitute at 0.2 mg/mL in sterile PBS.

Neurofascin encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. Neurofascin undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.
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Specifications

Antigen Neurofascin
Applications Immunohistochemistry (Frozen), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene NFASC
Gene Accession No. O94856, P97685, Q810U3
Gene Alias AA387016; D430023G06Rik; DKFZp686P2250; KIAA0756; KIAA0756FLJ46866; mKIAA0756; neurofascin; neurofascin homolog; NF; Nfasc; NRCAML
Gene Symbols NFASC
Host Species Chicken
Immunogen Mouse myeloma cell line NS0-derived recombinant rat Neurofascin Ile25-Ala1031.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116690, 23114, 269116
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgY
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