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Invitrogen™ Neurogenin 1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA591933

Product Code. 16558091

  • € 520.00 / 100µL

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Description

Description

Positive Samples: SH-SY5Y, THP-1, U-87MG, HepG2, Mouse testis; Cellular Location: Nucleus Immunogen sequence: MPARLETCIS DLDCASSSGS DLSGFLTDEE DCARLQQAAS ASGPPAPARR GAPNISRASE VPGAQDDEQE RRRRRGRTRV RSEALLHSLR RSRRVKANDR ERNRMHNLNA ALDALRSVLP SFPDDTKLTK IETLRFAYNY IWALAETLRL ADQGLPGGGA RERLLPPQCV PCLPGPPSPA SDAESWGSGA AAASPLSDPS SPAASEDFTY RPGDPVFSFP SLPKDLLHTT PCFIPYH.

Neurogenin 1 is a basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Neurogenin 1
Polyclonal
Unconjugated
NEUROG1
AKA; ATH4C; basic helix-loop-helix transcription factor; bHLHa6; cb260; chunp6899; class A basic helix-loop-helix protein 6; Helix-loop-helix protein mATH-4C; Math4C; Neurod3; NEUROG1; Neurogenic basic-helix-loop-helix protein; neurogenic differentiation 3; neurogenic differentiation factor 3; neurogenin; neurogenin 1; neurogenin related protein-1; neurogenin-1; Neurogenin-related protein 1; NGN; Ngn1; NGN-1; ngr1; transcription factor; Zath4c; zNgn1
Rabbit
Affinity Chromatography
RUO
18014, 4762
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot
0.28 mg/mL
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
P70660, Q92886
NEUROG1
Recombinant fusion protein containing a sequence corresponding to amino acids 1-237 of human NEUROG1 (Q92886).
100 μL
Primary
Human, Mouse
Antibody
IgG
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