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Invitrogen™ Neuropoietin Polyclonal Antibody
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Product Code. 30534466
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Quantity:
100 μg
Unit Size:
100µg
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30534466 100 μg 100µg
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Product Code. 30534466 Supplier Invitrogen™ Supplier No. PA5148620

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Description

Goat Polyclonal Antibody

Reconstitute at 0.2 mg/mL in sterile PBS.

Neuropoietin is a newly identified member of the IL-6 cytokine family. Members of this family, including IL-6, IL-11, oncostatin M, leukemia inhibitory factor (LIF), cardiotrophin-1 (CT-1), cardiotrophin-like cytokine, and CNTF, display a four-helix bundle structure, and signal through gp130-containing receptor complexes. Neuropoietin, which is predominantly expressed in neuroepithelia during embryonic life, acts through a receptor complex formed of a CNTF receptor-alpha component, gp 130, and LIF receptor. Like CNTF, it promotes the survival of embryonic motor neurons, and could increase the proliferation of neural precursor cells in the presence of EGF and FGF-2. Interestingly, the human neuropoietin gene has evolved toward a pseudogene, suggesting that alternative signaling via CNTF is an effective compensatory pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Neuropoietin
Applications Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with trehalose and no preservative
Gene Ctf2
Gene Accession No. P83714
Gene Alias cardiotrophin 2; cardiotrophin-2; CT-2; Ctf2; CTF2P; Gm494; Neuropoietin; Np
Gene Symbols Ctf2
Host Species Goat
Immunogen E. coli-derived recombinant mouse Neuropoietin/NP, Ala23-Ala204.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 244218
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Lyophilized
Isotype IgG
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