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NF-H Antibody (NE14), Alexa Fluor™ 350, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-47834AF350

Product Code. 18152448

  • € 573.00 / 0.10mL

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Description

Description

NF-H Monoclonal specifically detects NF-H in Human, Mouse, Rat, Porcine, Bovine, Chicken, Feline, Guinea Pig, Gerbil, Rabbit samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

NF-H
Monoclonal
Alexa Fluor 350
50 mM sodium borate with 0.05% sodium azide
NEFH
Crude neurofilament preparation from porcine spinal cord
0.1 mL
Primary
This monoclonal antibody reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). It reacts specifically with the phosphorylated KSP/KEP segment at the C-terminus of the heavy subunit (NF-H) of neurofilaments. After dephosphorylation of neurofilaments with alkaline phosphatase, this Ab no longer binds. Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Store at 4°C in the dark.
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)
NE14
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin
200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H
Mouse
Protein A or G purified
Autophagy, Cellular Markers, Cytoskeleton Markers, Neurodegeneration, Neurofilaments, Neuronal Cell Markers, Neuroscience
4744.0
Human, Mouse, Rat, Pig, Chicken, Feline, Guinea Pig, Gerbil, Primate, Rabbit
IgG1 κ
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